MSDS Number: B5056 * * * * * Effective Date: 03/14/07 * * * * *
Supercedes: 08/10/04

BROMOPHENOL BLUE

1. Product Identification

Synonyms: 3,3',5,5'-Tetrabromophenol sulfonphthalein;
4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromophenol]S ,S dioxide

CAS No.: 115-39-9
Molecular Weight: 670.02

Chemical Formula: C19H10Br4O5S
Product Codes: D293

2. Composition/Information on Ingredients

Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------------ ---------

Bromophenol Blue 115-39-9 90 - 100% Yes

3. Hazards Identification

Emergency Overview
--------------------------

CAUTION! MAY BE HARMFUL IF SWALLOWED OR INHALED. MAY CAUSE IRRITATION
TO SKIN, EYES, AND RESPIRATORY TRACT.

SAF-T-DATA(tm) Ratings (Provided here for your
convenience)

-----------------------------------------------------------------------------------------------------------

Health Rating: 1 - Slight
Flammability Rating: 1 - Slight

Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab
Protective Equip: GOGGLES; LAB COAT; PROPER GLOVES
Storage Color Code:
Green (General Storage)

Potential Health Effects
----------------------------------

Inhalation:
May cause irritation to the respiratory tract.
Symptoms may include coughing and shortness of breath.
Ingestion:

Effects not determined. Large oral doses may cause irritation to the
gastrointestinal tract.
Skin Contact:
May cause irritation with
redness and pain.
Eye Contact:
May cause irritation, redness
and pain.
Chronic Exposure:
Not determined.
Aggravation
of Pre-existing Conditions:
No information found.

4. First Aid Measures

Inhalation:
Remove to fresh air. Get medical attention
for any breathing difficulty.
Ingestion:
Induce vomiting
immediately as directed by medical personnel. Never give anything by mouth to
an unconscious person. Get medical attention.
Skin Contact:

Immediately flush skin with plenty of water for at least 15 minutes.
Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly
clean shoes before reuse. Get medical attention if irritation develops.

Eye Contact:
Immediately flush eyes with plenty of water for at
least 15 minutes, lifting upper and lower eyelids occasionally. Get medical
attention if irritation persists.

5. Fire Fighting Measures

Fire:
As with most organic solids, fire is possible at
elevated temperatures or by contact with an ignition source.

Explosion:
Fine dust dispersed in air in sufficient
concentrations, and in the presence of an ignition source is a potential dust
explosion hazard.
Fire Extinguishing Media:
Water spray, dry
chemical, alcohol foam, or carbon dioxide.
Special Information:

In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.

6. Accidental Release Measures

Remove all sources of ignition. Ventilate area of leak or spill.
Wear appropriate personal protective equipment as specified in Section 8.
Spills: Clean up spills in a manner that does not disperse dust into the air.
Use non-sparking tools and equipment. Reduce airborne dust and prevent
scattering by moistening with water. Pick up spill for recovery or disposal
and place in a closed container.

7. Handling and Storage

Keep in a tightly closed container. Protect from physical damage.
Store in a cool, dry, ventilated area away from sources of heat, moisture and
incompatibilities. Containers of this material may be hazardous when empty
since they retain product residues (dust, solids); observe all warnings and
precautions listed for the product.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
None established.

Ventilation System:
A system of local and/or general exhaust is
recommended to keep employee exposures as low as possible. Local exhaust
ventilation is generally preferred because it can control the emissions of the
contaminant at its source, preventing dispersion of it into the general work
area. Please refer to the ACGIH document, Industrial Ventilation, A Manual
of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
For conditions of use
where exposure to dust or mist is apparent and engineering controls are not
feasible, a particulate respirator (NIOSH type N95 or better filters) may be
worn. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are
present, use a NIOSH type R or P filter. For emergencies or instances where
the exposure levels are not known, use a full-face positive-pressure,
air-supplied respirator. WARNING: Air-purifying respirators do not protect
workers in oxygen-deficient atmospheres.
Skin Protection:
Wear
protective gloves and clean body-covering clothing.
Eye Protection:

Use chemical safety goggles. Maintain eye wash fountain and quick-drench
facilities in work area.

9. Physical and Chemical Properties

Appearance:
Tan to orange, light pink to purple or red
crystalline powder.
Odor:
Slightly amine to odorless.

Solubility:
0.4g/100g water @ 20C (68F).
Specific
Gravity:
No information found.
pH:
No information
found.
% Volatiles by volume @ 21C (70F):
0
Boiling
Point:
279C (534F)
Melting Point:
273C (523F)

Vapor Density (Air=1):
No information found.
Vapor
Pressure (mm Hg):
No information found.
Evaporation Rate
(BuAc=1):
No information found.

10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and
storage.
Hazardous Decomposition Products:
Burning may produce
bromines, sulfur oxides, carbon dioxide, and carbon monoxide.
Hazardous
Polymerization:
Will not occur.
Incompatibilities:

Strong oxidizers.
Conditions to Avoid:
Heat, flames,
ignition sources and incompatibles.

11. Toxicological Information

No LD50/LC50 information found relating to normal routes of
occupational exposure. Investigated as a mutagen.

--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Bromophenol Blue (115-39-9) No No None

12. Ecological Information

Environmental Fate:
No information found.

Environmental Toxicity:
No information found.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be
managed in an appropriate and approved waste disposal facility. Processing,
use or contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations. Dispose of container and unused contents in accordance with
federal, state and local requirements.

14. Transport Information

Not regulated.

15. Regulatory Information

--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Bromophenol Blue (115-39-9) Yes Yes Yes Yes

--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Bromophenol Blue (115-39-9) Yes Yes No Yes

--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Bromophenol Blue (115-39-9) No No No No

--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Bromophenol Blue (115-39-9) No No No

Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)

Australian Hazchem Code: None allocated.

Poison Schedule: None allocated.
WHMIS:
This MSDS
has been prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the
CPR.

16. Other Information

NFPA Ratings: Health: 1 Flammability: 1
Reactivity: 0
Label Hazard Warning:
CAUTION! MAY BE
HARMFUL IF SWALLOWED OR INHALED. MAY CAUSE IRRITATION TO SKIN, EYES, AND
RESPIRATORY TRACT.
Label Precautions:
Avoid contact with eyes,
skin and clothing.
Avoid breathing dust.
Keep container closed.
Use
with adequate ventilation.
Wash thoroughly after
handling.

Label First Aid:
If inhaled, remove to fresh
air. Get medical attention for any breathing difficulty. If swallowed, induce
vomiting immediately as directed by medical personnel. Never give anything by
mouth to an unconscious person. In case of contact, immediately flush eyes or
skin with plenty of water for at least 15 minutes. Get medical attention if
irritation develops or persists.
Product Use:
Laboratory
Reagent.
Revision Information:
MSDS Section(s) changed since
last revision of document include: 3.
Disclaimer:

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Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.

************************************************************************************************

Prepared by: Environmental Health & Safety
Phone Number:
(314) 654-1600 (U.S.A.)