Material Safety Data Sheet
    Pepsin (powder)
ACC# 01166
  
    | 
Section 1 - Chemical Product and Company Identification | 
  
MSDS Name: Pepsin (powder)
Catalog Numbers:
     AC417071000, AC417075000
Synonyms:
     Pepsin A; Lactated Pepsin; Pepsin Fortior; Lactated Pepsin Elixir;
     Pepsin 3; E.C. 3.4.1; E.C. 3.4.23.1; Elixer lactate of pepsin
Company Identification:
 
 
 
 
 
 
 
Acros Organics N.V.
 
 
 
 
 
 
 
One Reagent Lane
 
 
 
 
 
 
 
Fair Lawn, NJ  07410
For information in North America, call:   800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
  
    | 
Section 2 - Composition, Information on Ingredients
 | 
  | CAS# | 
    Chemical Name | 
    Percent | 
    EINECS/ELINCS | 
|    9001-75-6 | 
Pepsin A | 
   100    | 232-629-3 | 
  
    | 
Section 3 - Hazards Identification
 | 
EMERGENCY OVERVIEW
Appearance: light yellow solid.
 Warning! May cause allergic respiratory reaction.
May cause allergic skin reaction. May cause eye and skin irritation.
Ingestion may result in an allergic reaction.
Target Organs: Respiratory system, skin.
Potential Health Effects
     
Eye:
          May cause eye irritation.
     
Skin:
          May cause skin irritation.
     
Ingestion:
          May cause allergic reaction characterized by a rash.
     
Inhalation:
          May cause asthmatic attacks due to allergic sensitization of the
          respiratory tract. May cause respiratory tract irritation.
     
Chronic:
          No information found.
  
    | 
Section 4 - First Aid Measures
 | 
     
Eyes:
          Immediately flush eyes with plenty of water for at least 15 minutes,
          occasionally lifting the upper and lower eyelids. Get medical aid imme
          diately.
     
Skin:
          Flush skin with plenty of water for at least 15 minutes while
          removing contaminated clothing and shoes. Get medical aid if
          irritation develops or persists.
     
Ingestion:
          Never give anything by mouth to an unconscious person. Get medical
          aid. Wash mouth out with water.
     
Inhalation:
          Get medical aid immediately. Remove from exposure and move to fresh
          air immediately. If not breathing, give artificial respiration. If
          breathing is difficult, give oxygen.
     
Notes to Physician:
          Treat symptomatically and supportively.
  
    | 
Section 5 - Fire Fighting Measures
 | 
     
General Information:
          As in any fire, wear a self-contained breathing apparatus in
          pressure-demand, MSHA/NIOSH (approved or equivalent), and full
          protective gear. Can burn in a fire, releasing toxic vapors.
     
Extinguishing Media:
          In case of fire, use water, dry chemical, chemical foam, or
          alcohol-resistant foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
                  Upper: Not available.
     
NFPA Rating:
(estimated) Health: 2; Flammability: 1; Instability: 0
  
    | 
Section 6 - Accidental Release Measures
 | 
     
General Information: Use proper personal protective equipment as indicated
                          in Section 8.
     
Spills/Leaks:
          Vacuum or sweep up material and place into a suitable disposal
          container. Clean up spills immediately, observing precautions in the
          Protective Equipment section. Avoid generating dusty conditions.
          Provide ventilation.
  
    | 
Section 7 - Handling and Storage
 | 
     
Handling:
          Wash thoroughly after handling. Remove contaminated clothing and
          wash before reuse. Minimize dust generation and accumulation. Do not
          get on skin or in eyes. Avoid ingestion and inhalation. Use with
          adequate ventilation.
     
Storage:
          Store in a tightly closed container. Store in a cool, dry area away
          from incompatible substances.
  
    | 
Section 8 - Exposure Controls, Personal Protection
 | 
     
Engineering Controls:
          Facilities storing or utilizing this material should be equipped
          with an eyewash facility and a safety shower. Use adequate
          ventilation to keep airborne concentrations low.
Exposure Limits
  | Chemical Name | 
    ACGIH | 
    NIOSH | 
    OSHA - Final PELs | 
| Pepsin A
 | 
none listed
 | 
none listed
 | 
none listed
 | 
     
OSHA Vacated PELs:
          Pepsin A:
             No OSHA Vacated PELs are listed for this chemical.
     
Personal Protective Equipment
                 
Eyes:
                       Wear appropriate protective eyeglasses or chemical
                       safety goggles as described by OSHA's eye and face
                       protection regulations in 29 CFR 1910.133 or European
                       Standard EN166.
                 
Skin:
                       Wear appropriate protective gloves to prevent skin
                       exposure.
             
Clothing:
                       Wear appropriate protective clothing to prevent skin
                       exposure.
          
Respirators:
                       A respiratory protection program that meets OSHA's 29
                       CFR 1910.134 and ANSI Z88.2 requirements or European
                       Standard EN 149 must be followed whenever workplace
                       conditions warrant respirator use. Follow the OSHA
                       respirator regulations found in 29 CFR 1910.134 or
                       European Standard EN 149. Use a NIOSH/MSHA or
                       European Standard EN 149 approved respirator if
                       exposure limits are exceeded or if irritation or
                       other symptoms are experienced.
  
    | 
Section 9 - Physical and Chemical Properties
 | 
Physical State:  Solid
Appearance:      light yellow
Odor:            Not available.
pH:              Not available.
Vapor Pressure:  Negligible
Vapor Density:   Not available.
Evaporation Rate:Negligible.
Viscosity:       Not available.
Boiling Point:   Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility:      Soluble.
Specific Gravity/Density:Not available.
Molecular Formula:Not applicable.
Molecular Weight:34,500
  
    | 
Section 10 - Stability and Reactivity
 | 
     
Chemical Stability:
          Stable.
     
Conditions to Avoid:
          Incompatible materials.
     
Incompatibilities with Other Materials:
          Strong oxidizing agents, alcohols, alkalis, tannin, heavy metal
          salts.
     
Hazardous Decomposition Products:
          Nitrogen oxides, carbon monoxide, carbon dioxide.
     
Hazardous Polymerization: Will not occur.
  
    | 
Section 11 - Toxicological Information
 | 
     
RTECS#:
     
CAS# 9001-75-6:
SC6132000
     
LD50/LC50:
          Not available.
     
Carcinogenicity:
       CAS#    9001-75-6:
          Not listed by ACGIH, IARC, NTP, or CA Prop 65.
     
Epidemiology:
          No data available.
     
Teratogenicity:
          No data available.
     
Reproductive Effects:
          No data available.
     
Mutagenicity:
DNA damage: hamster Fibroblast = 1000 ppm.
     
Neurotoxicity:
          No data available.
     
Other Studies:
  
    | 
Section 12 - Ecological Information
 | 
          No information available.
  
    | 
Section 13 - Disposal Considerations
 | 
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
  
    | 
Section 14 - Transport Information
 | 
  |        | 
    US DOT | 
    Canada TDG | 
| Shipping Name: | 
Not regulated as a hazardous material | 
No information available. | 
| Hazard Class: | 
 | 
 | 
| UN Number: | 
 | 
 | 
| Packing Group: | 
 | 
 | 
  
    | 
Section 15 - Regulatory Information
 | 
 US FEDERAL
     
TSCA
     CAS# 9001-75-6 is listed on the TSCA inventory.
        
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
        
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
        
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
        
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
        
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
        
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
        
SARA Codes
     CAS # 9001-75-6: immediate.
        
Section 313
     No chemicals are reportable under Section 313.
     
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
     
Clean Water Act:
     None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
     None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
     
OSHA:
     None of the chemicals in this product
are considered highly hazardous by OSHA.
 
STATE
          CAS#    9001-75-6 is not present on
     state lists from CA, PA, MN, MA, FL, or NJ.
 
California Prop 65
     
California No Significant Risk Level:
     None of the chemicals in this product are listed.
 
European/International Regulations
     European Labeling in Accordance with EC Directives
          Hazard Symbols:
      XN
          
Risk Phrases:
     R 36/37/38  Irritating to eyes, respiratory system and skin.          
     R 42  May cause sensitization by inhalation.                          
          
Safety Phrases:
     S 22  Do not breathe dust.                                            
     S 24  Avoid contact with skin.                                        
     S 26  In case of contact with eyes, rinse immediately with plenty of  
     water and seek medical advice.                                        
     S 36/37  Wear suitable protective clothing and gloves.                
   
WGK (Water Danger/Protection)
     CAS# 9001-75-6: 0
   Canada - DSL/NDSL
          None of the chemicals in this product are listed on the DSL or NDSL list.
   Canada - WHMIS
     This product has a WHMIS classification of D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
   Canadian Ingredient Disclosure List
  
    | 
Section 16 - Additional Information
 | 
     MSDS Creation Date:  9/02/1997  
Revision #4 Date: 10/03/2005
     The information above is believed to be accurate and represents the best
     information currently available to us. However, we make no warranty of
     merchantability or any other warranty, express or implied, with respect to
     such information, and we assume no liability resulting from its use. Users
     should make their own investigations to determine the suitability of the
     information for their particular purposes. In no event shall Fisher be liable
     for any claims, losses, or damages of any third party or for lost profits
     or any special, indirect, incidental, consequential or exemplary
     damages, howsoever arising, even if Fisher has been advised of
     the possibility of such damages.